Project conducted by the Team of Professor Miguel Castanho wins Science Without Borders Programme Scholarship
Prof. Doutor Miguel Castanho, Director of the Biochemistry Institute of FMUL and Coordinator of the Physical Biochemistry Unit of the IMM
Following the several scientific collaboration projects that Professor Miguel Castanho (Director of the Biochemistry Institute of FMUL and Coordinator of the Physical Biochemistry Unit of the IMM) has had with the Federal University of Rio de Janeiro (Universidade Federal do Rio de Janeiro - UFRJ), particularly on the study of the Dengue virus, the UFRJ invited him to join its postgraduate programme in Medical Biochemistry and make a joint application to the Science Without Borders (CNPq/CAPES, Brazil). The application was approved and he was awarded the status of Special Visiting Researcher at UFRJ. The work plan has three components:
1. An extensive research programme on the Dengue virus. It includes a “sandwich” Ph.D. and a post-doc scholarship to interconnect the Portuguese and Brazilian laboratories.
2. Teaching associated to the postgraduate Medical Biochemistry programme of the Federal University of Rio de Janeiro. This postgraduate programme is one of the few programmes in Brazil evaluated with top marks by the CAPES agency.
3. Outreaching/extension activities outside the academic environment.
Examples of posters of Dengue prevention public campaigns in Brazil
Project Title:
Innovative approaches in studies of the peptide-membrane interaction in systems of biological and clinical interest: focusing on the fusion of the dengue virus and on the teaching of structural biochemistry
The Scientific Project:
The scientific project to be conducted focuses on the entry mechanisms of the DENV viral genome on cells, as the process of fusion pore formation has never been directly observed or proven by specific scientific data. DENV fusion has been attributed solely to the action of protein E and this assumption has never been questioned, as far as it is possible to know. The hypothesis that the proposed project will test and study is that the capsid protein (C) of DENV, regarded as an essentially structural protein constituent of the viral capsid, may have a functional role in viral infection by acting as a transfection agent of viral RNA
Brazilian team involved in the project:
Professor Andrea Thompson da Poian (Host Researcher, UFRJ)
Thais M. Conceição
Fábio R. Oliveira
Glauce M. Barbosa
Examples of posters of Dengue prevention public campaigns in Brazil
What is the Science Without Borders Project?
Science Without Borders is a Brazilian programme that seeks to foster the consolidation, expansion and internationalization of science and technology, innovation and competitiveness through exchange and international mobility.
The project envisages the use of up to one hundred and one thousand scholarships over four years to encourage exchanges, so that undergraduate and postgraduate students may carry out an internship abroad in order to be familiar with competitive educational systems with regard to technology and innovation. In addition, it seeks to attract foreign researchers who may wish to settle in Brazil or establish partnerships with Brazilian researchers in priority areas established in the programme.
Current projects here
Prof. Doutor Miguel Castanho, Director of the Biochemistry Institute of FMUL and Coordinator of the Physical Biochemistry Unit of the IMM
Following the several scientific collaboration projects that Professor Miguel Castanho (Director of the Biochemistry Institute of FMUL and Coordinator of the Physical Biochemistry Unit of the IMM) has had with the Federal University of Rio de Janeiro (Universidade Federal do Rio de Janeiro - UFRJ), particularly on the study of the Dengue virus, the UFRJ invited him to join its postgraduate programme in Medical Biochemistry and make a joint application to the Science Without Borders (CNPq/CAPES, Brazil). The application was approved and he was awarded the status of Special Visiting Researcher at UFRJ. The work plan has three components:
1. An extensive research programme on the Dengue virus. It includes a “sandwich” Ph.D. and a post-doc scholarship to interconnect the Portuguese and Brazilian laboratories.
2. Teaching associated to the postgraduate Medical Biochemistry programme of the Federal University of Rio de Janeiro. This postgraduate programme is one of the few programmes in Brazil evaluated with top marks by the CAPES agency.
3. Outreaching/extension activities outside the academic environment.
Examples of posters of Dengue prevention public campaigns in Brazil
Project Title:
Innovative approaches in studies of the peptide-membrane interaction in systems of biological and clinical interest: focusing on the fusion of the dengue virus and on the teaching of structural biochemistry
The Scientific Project:
The scientific project to be conducted focuses on the entry mechanisms of the DENV viral genome on cells, as the process of fusion pore formation has never been directly observed or proven by specific scientific data. DENV fusion has been attributed solely to the action of protein E and this assumption has never been questioned, as far as it is possible to know. The hypothesis that the proposed project will test and study is that the capsid protein (C) of DENV, regarded as an essentially structural protein constituent of the viral capsid, may have a functional role in viral infection by acting as a transfection agent of viral RNA
Brazilian team involved in the project:
Professor Andrea Thompson da Poian (Host Researcher, UFRJ)
Thais M. Conceição
Fábio R. Oliveira
Glauce M. Barbosa
Examples of posters of Dengue prevention public campaigns in Brazil
What is the Science Without Borders Project?
Science Without Borders is a Brazilian programme that seeks to foster the consolidation, expansion and internationalization of science and technology, innovation and competitiveness through exchange and international mobility.
The project envisages the use of up to one hundred and one thousand scholarships over four years to encourage exchanges, so that undergraduate and postgraduate students may carry out an internship abroad in order to be familiar with competitive educational systems with regard to technology and innovation. In addition, it seeks to attract foreign researchers who may wish to settle in Brazil or establish partnerships with Brazilian researchers in priority areas established in the programme.
Current projects here
