Luísa Lopes, lead researcher at the João Lobo Antunes Institute of Molecular Medicine (iMM), coordinated a study published in Molecular Psychiatry about the processes that lead to memory loss associated with ageing.
The research, which has been developed for three years now, shows that, according to what Luísa Lopes told Diário de Notícias there are "specific changes in signalling in the circuits involved in memory that induce an abnormal response of the nerve cells in the brain that is associated with ageing".
To this newspaper, the first author of the work and student of the Lisbon BioMed PhD program at the iMM, Mariana Temido, said: "The mere fact of altering the quantity of the adenosine receptor in neurons in the hippocampus and the cortex has led to a profile that we have labelled early ageing, since it causes cognitive shortfalls and changes in neuronal transmission".
This discovery "opens up new perspectives for the design of drugs that regulate this aberrant signalling (...), particularly the caffeine family that has also been tested effectively in the study".
Read the article from Diário de Notícias here.
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Image Credits: Diário de Notícias | Sara Matos / Global Images
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André Rodrigues
Editorial Team
The research, which has been developed for three years now, shows that, according to what Luísa Lopes told Diário de Notícias there are "specific changes in signalling in the circuits involved in memory that induce an abnormal response of the nerve cells in the brain that is associated with ageing".
To this newspaper, the first author of the work and student of the Lisbon BioMed PhD program at the iMM, Mariana Temido, said: "The mere fact of altering the quantity of the adenosine receptor in neurons in the hippocampus and the cortex has led to a profile that we have labelled early ageing, since it causes cognitive shortfalls and changes in neuronal transmission".
This discovery "opens up new perspectives for the design of drugs that regulate this aberrant signalling (...), particularly the caffeine family that has also been tested effectively in the study".
Read the article from Diário de Notícias here.
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Image Credits: Diário de Notícias | Sara Matos / Global Images
s
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André Rodrigues
Editorial Team
