University of Pisa Summer School
Pisa, July 4th - July 9th 2022
Cardiovascular Summer School: Clinical & Experimental - VIII Edition
Course Director: Prof. Raffaele De Caterina
Scientific Committee: Dr Rosalinda Madonna, Dr Doralisa Morrone, Prof. Carlo Palombo
School of Medicine
Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine
University of Pisa
VENUE: POLO CONGRESSUALE LE BENEDETTINE - PIAZZA SAN PAOLO A RIPA D’ARNO, 16 Pisa
July 4th
8:00 – 8:30 Registration of participants
8:30 – 9:00 The international promotion of teaching activities at the University of Pisa
Francesco Marcelloni, Pisa
The Summer School in the Department activity
Angelo Gemignani, Pisa
Introduction to the course
Raffaele De Caterina, Pisa
INTRODUCTION to CARDIOVASCULAR MEDICINE and RESEARCH
09:00 – 10:00 Keynote Opening Lecture: Methodology of experimental and clinical medicine: evidence-based medicine, personalized medicine, systems medicine
Gian Franco Gensini, Florence
10:00 – 10:45 The global burden of cardiovascular disease in the XXI century
Aldo Pietro Maggioni, Florence
Coffee break
11:15 – 12:15 Keynote Lecture: Drug development in the COVID-19 era
Peter Ferdinandy, Semmelweis University, Budapest
12:15 – 13:15 Keynote Lecture: Current and future directions in cardiovascular research
Filippo Crea, Rome
Lunch break
PRINCIPLES in CARDIOVASCULAR PHYSIOLOGY
15:00 – 16:00 Left and right heart mechanics
Fabio Recchia, Pisa
16:00 – 17:00 Principles of myocardial metabolism
Paolo G. Camici, Milan
17:00 – 18:00 Principles of exercise physiology
Carlo Capelli, Verona
July 5th
THE CORONARY CIRCULATION and CORONARY ARTERY DISEASE (I part)
9:00 – 9:45 Pathophysiology of coronary macro- and microcirculation
Danilo Neglia, Pisa
9:45 – 10:30 Ischemic heart disease: the atherothrombotic background
Raffaele De Caterina, Pisa
Coffee break
11:00 – 12:00 Keynote Lecture: Redefining ischemic heart disease: from “coronary stenosis” to myocardial ischemia:
Mario Marzilli, Pisa
Lunch break
THE CORONARY CIRCULATION and CORONARY ARTERY DISEASE (II part)
15:00 – 15:30 Principles of diagnosis of myocardial ischemia
Doralisa Morrone, Pisa
15:30 – 16:00 Principles of treatment of acute coronary syndromes
Marco De Carlo, Pisa
16:00 – 16:30 Principles of treatment of chronic coronary artery disease
Giacinta Guarini, Pisa
16:30 – 17:30 Keynote Lecture: Antithrombotic therapy in patients with coronary artery disease
Steen Dalby Kristensen, Aarhus, Denmark
* * * * *
17:30 – 18:00 The University of Pisa for foreign students
Paola Cappellini, Pisa
July 6th
ANTITHROMBOTIC DRUGS: FROM BASIC PHARMACOLOGY TO CLINICAL USE
09:00 – 09:45 Principles of hemostasis: platelets, coagulation and fibrinolysis
Rossella Marcucci, Florence
9:45 – 10:30 Antithrombotic therapy in atrial fibrillation
Raffaele De Caterina, Pisa
Coffee break
11:00 – 12:00 Keynote Lecture: Aspirin: yesterday, today and tomorrow: long life to the old lady!
Carlo Patrono, Rome
* * * * *
12:30 – 13:00 The University of Pisa Museums System
Chiara Bodei, Pisa
MUSEUMS AFTERNOON
15:00 – 18:00 Guided tours of the Anatomy Museum and other museums of the University of Pisa
19:30 – 23:00 Social Dinner
July 7th
IMAGING IN CARDIOVASCULAR DIAGNOSIS AND DECISION MAKING
9:00 – 9:45 Carotid plaque vulnerability and tissue characterization by ultrasound
Isabel Gonçalves, Lund, Sweden
9:45-10:30 Imaging of the heart: nuclear cardiology from the origin to the XXI century:
Alessia Gimelli and Paolo Marzullo, Pisa
Coffee break
11:00 –11:45 Advanced imaging of the heart and coronary vessels: principles of cardiac magnetic resonance and angio-computed tomography
Dante Chiappino, Pisa-Massa
11:45 – 12:30 Thoracic ultrasound: pathophysiological background and clinical implications
Luna Gargani, Pisa
Lunch break
PERSPECTIVES in HEART FAILURE RESEARCH
14:00 –15:00 Keynote lecture: Pathophysiology and risk stratification in heart failure
Piergiuseppe Agostoni, Milan
15:00 – 15:45 Definition, classification, pathophysiology and treatment of pulmonary hypertension: Rosalinda Madonna, Pisa
15:45 – 16:30 The cardiopulmonary exercise test: from pathophysiology to patients phenotyping and rehabilitation
Claudio Passino, Pisa
16:30 – 17:30 The cardiovascular system in obesity
Andrea Natali, Pisa
July 8th
ARTERIAL DISEASE AND HYPERTENSION
9:00 – 10:00 Assessment of large artery structure and function: from pathophysiology to clinical applications
Carlo Palombo, Pisa
10:00 – 11:00 Microvessels and endothelial dysfunction: from bench to bedside:
Agostino Virdis, Pisa and Enrico Agabiti Rosei, Brescia
Coffee break
11:30 – 12:15 Aortic disease: pathophysiology, risk stratification and management:
Riccardo Liga, Pisa
12:15 – 13:15 Seminal steps and perspectives in hypertension research: from Riva Rocci and Bjorn Folkow to the XXI century
Stefano Taddei, Pisa
Lunc break
FOCUS on CARDIOMYOPATHIES
15:00 – 15:45 Hypertrophic cardiomyopathy
Iacopo Olivotto, Florence
15:45 – 16:30 Infiltrative cardiomyopathies: the amyloidosis model
Michele Emdin, Pisa
16:30 – 17:15 Diabetic heart disease
Stefano Del Prato and Fabio Lattanzi, Pisa
17:15 – 18:00 The Cardio-Renal syndrome: a unifying paradigm for cardiometabolic disease and heart failure?
Anna Solini, Pisa
July 9th
PERSPECTIVES in ARRHTHMIAS and VALVULAR DISEASE
9:00 – 10:00 Keynote Lecture: Risk stratification and prevention of cardiac sudden death in the young
Silvia Priori, Pavia
10:00 – 10:45 Perspectives in arrhythmia ablation research: new diagnostic tools, new devices, clinical improvement?
Giulio Zucchelli and Maria Grazia Bongiorni, Pisa
Coffee break
11:15 – 12:00 New approaches to treatment of aortic valve disease
Anna Sonia Petronio, Pisa
12:00 – 13:00 Closing Keynote Lecture: New approaches to treatment of mitral valve disease
Carlo Di Mario, Florence
13:00 Closing remarks
Raffaele De Caterina and Carlo Palombo, Pisa
The END