The Newsletter intends to give its readers a perspective of the scientific production carried out at the Lisbon Academic Medical Center (CAML), which includes the Faculty of Medicine of the University of Lisbon, the Santa Maria Hospital and the Institute of Molecular Medicine João Lobo Antunes.
The databases used were Pubmed, Web of Science and Scopus
Access to full text of the articles is possible when they were published in open accessm or in magazines subscribed by FMUL (IP recognition)
Tsvetanov KA, et al. Genetic FTD Initiative, GENFI.
Brain functional network integrity sustains cognitive function despite atrophy in presymptomatic genetic frontotemporal dementia
Alzheimer’s & Dementia. 2020 Nov 20. doi: 10.1002/alz.12209.
Chaves Loureiro C, Branco Ferreira M, Ferreira J, Lima R, Marques J, Sokolova A, Tonin FS, Duarte Ramos F.
Reducing oral corticosteroids in severe asthma (ROSA Project): a nationwide Portuguese consensus
Pulmonology. 2020 Nov 8:S2531-0437(20)30217-8. doi: 10.1016/j.pulmoe.2020.10.002.
Kaushik M, Ponte C, Mollan SP.
Current advances in giant cell arteritis
Current Opinion in Neurology. 2020 Nov 20. doi: 10.1097/WCO.0000000000000889.
Cavaco M, Andreu D, Castanho MARB.
The challenge of peptide proteolytic stability studies: scarce data, difficult readability, and the need for harmonization.
Angewandte Chemie (Intern. Ed. Engl.) 2020 Nov 17. doi: 10.1002/anie.202006372. Epub ahead of print. PMID: 33200441.
Adams D, et al ; patisiran Global OLE study group.
Long-term safety and efficacy of patisiran for hereditary transthyretin-mediated amyloidosis with polyneuropathy: 12-month results of an open-label extension study
Lancet Neurology. 2020 Nov 16:S1474-4422(20)30368-9. doi: 10.1016/S1474-4422(20)30368-9.
Marttinen M, Ferreira CB, Paldanius KMA, Takalo M, Natunen T, Mäkinen P, Leppänen L, Leinonen V, Tanigaki K, Kang G, Hiroi N, Soininen H, Rilla K, Haapasalo A, Hiltunen M.
Presynaptic vesicle protein SEPTIN5 regulates the degradation of APP C-Terminal fragments and the levels of Aβ
Cells. 2020 Nov 15;9(11):E2482. doi: 10.3390/cells9112482. PMID: 33203136.
Fiala GJ, Gomes AQ, Silva-Santos B.
From thymus to periphery: Molecular basis of effector γδ-T cell differentiation
Immunological Reviews. 2020 Nov 15. doi: 10.1111/imr.12918.
Dourado E, Ferro M, Sousa Guerreiro C, Fonseca JE.
Diet as a Modulator of Intestinal Microbiota in Rheumatoid Arthritis
Nutrients. 2020 Nov 14;12(11):E3504. doi: 10.3390/nu12113504
Lopes N, Silva-Santos B.
Functional and metabolic dichotomy of murine γδ T cell subsets in cancer immunity
European Journal of Immunology. 2020 Nov 14. doi: 10.1002/eji.201948402
De Geyter C, Wyns C, Calhaz-Jorge C, de Mouzon J, Ferraretti AP, Kupka M, Nyboe Andersen A, Nygren KG, Goossens V.
20 years of the European IVF-monitoring Consortium registry: what have we learned? A comparison with registries from two other regions.
Human Reproduction. 2020 Nov 14:deaa250. doi: 10.1093/humrep/deaa250.
Marques JG.
Temporal lobe epilepsy mimicking schizoaffective disorder in patients with cavum septi pellucidi.
Primary Care Companion for CNS Disorder. 2020 Nov 12;22(6):20l02613. doi: 10.4088/PCC.20l02613. PMID: 33185987.
Bonavita E, et al.
Antagonistic inflammatory phenotypes dictate tumor fate and response to immune checkpoint blockade
Immunity. 2020 Nov 10:S1074-7613(20)30461-1. doi: 10.1016/j.immuni.2020.10.020.
Fonte M, Tassi N, Fontinha D, Bouzón-Arnáiz I, Ferraz R, Araújo MJ, Fernàndez-Busquets X, Prudêncio M, Gomes P, Teixeira C.
4,9-diaminoacridines and 4-aminoacridines as dual-stage antiplasmodial hits
ChemMedChem. 2020 Nov 20. doi: 10.1002/cmdc.202000740.
Peixoto C, Lopes MB, Martins M, Costa L, Vinga S.
TCox: correlation-based regularization applied to Colorectal Cancer survival data
Biomedicines. 2020 Nov 10;8(11):E488. doi: 10.3390/biomedicines8110488.
Reis D, Moura M, Freitas LC, Carvalhana S, Nogueira PJ, Gaio R, Marinho RT, Cortez-Pinto H.
Predictive factors for long-term survival in patients with advanced hepatocellular carcinoma treated with Sorafenib
European Journal of Gastroenterology & Hepatology. 2020 Nov 10. doi: 10.1097/MEG.0000000000001974.
Burney P, et al.
Prevalence and population attributable risk for chronic airflow obstruction in a large multinational study
American Journal of Respiratory and Critical Care Medicine. 2020 Nov 10. doi: 10.1164/rccm.202005-1990OC. Epub ahead of print. PMID: 33171069.
Ribeiro NV, Melo RG, Guerra NC, Nobre Â, Fernandes RM, Pedro LM, Costa J, Pinto FJ, Caldeira D.
Fluoroquinolones are associated with increased risk of aortic aneurysm or dissection: systematic review and meta-analysis
Seminars in Thoracic and Cardiovascular Surgery. 2020 Nov 9:S1043-0679(20)30404-4. doi: 10.1053/j.semtcvs.2020.11.011.
José P, Teixeira FJ, Barão RC, Sens P, Abegão Pinto L.
Needling after XEN gel implant: What's the efficacy? A 1-year analysis
European Journal of Ophthalmology. 2020 Nov 8:1120672120963447. doi: 10.1177/1120672120963447.
Fogaça da Mata M, Rebelo M, Sousa HS, Rocha A, Miguel P, Oliveira Ramos F, Costa-Reis P.
Sinus node disfunction in an adolescent with systemic lupus erythematosus
Lupus. 2020 Nov 20:961203320974091. doi: 10.1177/0961203320974091.
Aguiar FLL, Santos NC, de Paula Cavalcante CS, Andreu D, Baptista GR, Gonçalves S.
Antibiofilm activity on Candida albicans and mechanism of action on biomembrane models of the antimicrobial Peptide Ctn
Int J Mol Sci. 2020 Nov 6;21(21):8339. doi: 10.3390/ijms21218339.
Setua S, Enguita FJ, Chora ÂF, Ranga-Prasad H, Lahree A, Marques S, Sundaramurthy V, Mota MM.
Disrupting Plasmodium UIS3-host LC3 interaction with a small molecule causes parasite elimination from host cells
Communications Biology. 2020 Nov 19;3(1):688. doi: 10.1038/s42003-020-01422-1.
Duarte GS, Rodrigues FB, Castelão M, Marques RE, Ferreira J, Sampaio C, Moore AP, Costa J.
Botulinum toxin type A therapy for hemifacial spasm
Cochrane Database of Systematic Reviews. 2020 Nov 19;11:CD004899. doi: 10.1002/14651858.CD004899.pub3.
Duarte GS, Rodrigues FB, Marques RE, Castelão M, Ferreira J, Sampaio C, Moore AP, Costa J.
Botulinum toxin type A therapy for blepharospasm
Cochrane Database of Systematic Reviews. 2020 Nov 19;11:CD004900. doi: 10.1002/14651858.CD004900.pub3. PMID: 33211907.
Macías-León J, Bermejo IA, Asín A, García-García A, Compañón I, Jiménez-Moreno E, Coelho H, Mangini V, Albuquerque IS, Marcelo F, Asensio JL, Bernardes GJL, Joshi HJ, Fiammengo R, Blixt O, Hurtado-Guerrero R, Corzana F
Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody
Chemical Communications (Cambridge). 2020 Nov 19. doi: 10.1039/d0cc06349e.
Lousa D, Pinto ART, Campos SRR, Baptista AM, Veiga AS, Castanho MARB, Soares CM.
Effect of pH on the influenza fusion peptide properties unveiled by constant-pH molecular dynamics simulations combined with experiment
Scientific Reports. 2020 Nov 18;10(1):20082. doi: 10.1038/s41598-020-77040-y.
Hespanhol V, Bárbara C.
Pneumonia mortality, comorbidities matter? Authors' answer
Pulmonology. 2020 Nov 17:S2531-0437(20)30212-9. doi: 10.1016/j.pulmoe.2020.09.005.
Mendes J, Ribeiro FJ, Ferreira TB.
Evaluation of posterior and total corneal astigmatism with colour-LED topography
Eye (Lond). 2020 Nov 17. doi: 10.1038/s41433-020-01278-z.
Machado A, Matos Silva P, Afreixo V, Caneiras C, Burtin C, Marques A.
Design of pulmonary rehabilitation programmes during acute exacerbations of COPD: a systematic review and network meta-analysis
European Respiratory Review. 2020 Nov 18;29(158):200039. doi: 10.1183/16000617.0039-2020.
Carvalho PD, Ruyssen-Witrand A, Marreiros A, Machado PM.
Long-term association between disease activity and disability in early axial spondyloarthritis: results from the DESIR cohort.
Arthritis Care & Research (Hoboken). 2020 Nov 18. doi: 10.1002/acr.24515
Katerenchuk V, Duarte GS, Martins E Pereira G, Fernandes RM, Ferreira JJ, Pinto FJ, Costa J, Caldeira D.
Satisfaction of patients with Nonvitamin K Anticoagulants compared to Vitamin K Antagonists: a systematic review and meta-analysis.
Thrombosis and Haemostasis. 2020 Nov 7. doi: 10.1055/s-0040-1716752.
Magro F, Doherty G, Peyrin-Biroulet L, Svrcek M, Borralho P, Walsh A, Carneiro F, Rosini F, de Hertogh G, Biedermann L, Pouillon L, Scharl M, Tripathi M, Danese S, Villanacci V, Feakins R.
ECCO Position Paper: Harmonization of the Approach to Ulcerative Colitis Histopathology
Journal of Crohn's and Colitis. 2020 Nov 7;14(11):1503-1511. doi: 10.1093/ecco-jcc/jjaa110.
Mello-Vieira J, Enguita FJ, de Koning-Ward TF, Zuzarte-Luís V, Mota MM.
Plasmodium translocon component EXP2 facilitates hepatocyte invasion
Nature Communications. 2020 Nov 6;11(1):5654. doi: 10.1038/s41467-020-19492-4.
Henriques P, Dello Iacono L, Gimeno A, Biolchi A, Romano MR, Arda A, Bernardes GJL, Jimenez-Barbero J, Berti F, Rappuoli R, Adamo R.
Structure of a protective epitope reveals the importance of acetylation of Neisseria meningitidis serogroup A capsular polysaccharide
Proceedings of the National Academy of Sciences USA. 2020 Nov 6:202011385. doi: 10.1073/pnas.2011385117.
Martinho AC, Marques IP, Messias AL, Santos T, Madeira MH, Sousa DC, Lobo C, Cunha-Vaz J.
Ocular and systemic risk markers for development of Macular Edema and Proliferative Retinopathy in Type 2 Diabetes: a 5-year longitudinal study
Diabetes Care. 2020 Nov 6:dc201125. doi: 10.2337/dc20-1125.
Miranda-Lourenço C, Ribeiro-Rodrigues L, Fonseca-Gomes J, Tanqueiro SR, Belo RF, Ferreira CB, Rei N, Ferreira-Manso M, de Almeida-Borlido C, Costa-Coelho T, Freitas CF, Zavalko S, Mouro FM, Sebastião AM, Xapelli S, Rodrigues TM, Diógenes MJ.
Challenges of BDNF-based therapies: from common to rare diseases
Pharmacology Research. 2020 Nov 5:105281. doi: 10.1016/j.phrs.2020.105281.
de Almeida Fuzeta M, Bernardes N, Oliveira FD, Costa AC, Fernandes-Platzgummer A, Farinha JP, Rodrigues CAV, Jung S, Tseng RJ, Milligan W, Lee B, Castanho MARB, Gaspar D, Cabral JMS, da Silva CL.
Scalable production of human mesenchymal stromal cell-derived extracellular vesicles under serum-/xeno-free conditions in a microcarrier-based bioreactor culture system
Frontiers in Cell and Developmental Biology. 2020 Nov 3;8:553444. doi: 10.3389/fcell.2020.553444.
Fonseca-Gomes J, Loureiro JA, Tanqueiro SR, Mouro FM, Ruivo P, Carvalho T, Sebastião AM, Diógenes MJ, Pereira MC.
In vivo bio-distribution and toxicity evaluation of polymeric and lipid-based nanoparticles: a potential approach for chronic diseases treatment
International Journal of Nanomedicine. 2020 Nov 5;15:8609-8621. doi: 10.2147/IJN.S267007.
Vilarinho R, Caneiras C, Montes AM.
Measurement properties of step tests for exercise capacity in COPD: A systematic review
Clinical Rehabilitation. 2020 Nov 6:269215520968054. doi: 10.1177/0269215520968054.
Hoyer D, Schmidt A, Pytlik A, Viehöfer L, Goncalves H, Amorim-Costa C, Bernardes J, Ayres-de-Campos D, Lobmaier SM, Schneider U.
Can fetal heart rate variability obtained from cardiotocography provide the same diagnostic value like from electrophysiological interbeat intervals?
Physiological Measure. 2020 Nov 4. doi: 10.1088/1361-6579/abc791.
Maleita D, Serras-Pereira R, Passos I, Elisa-Luís M, Alves M, Papoila AL, Brito C, Cunha JP, Tavares Ferreira J.
Retinal structural changes in preterm children without retinopathy of prematurity
Graefe's Archive for Clinical and Experimental Ophthalmology 2020 Nov 4. doi: 10.1007/s00417-020-04986-0.
Ferro JM.
Improving outcomes and decreasing costs for neurological diseases: mind the gap.
European Journal of Neurology. 2020 Nov 3. doi: 10.1111/ene.14625.
Wu H, Hariz M, Visser-Vandewalle V, et el.
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?
Molecular Psychiatry. 2020 Nov 3. doi: 10.1038/s41380-020-00933-x.
Foeldvari I, Klotsche J, Hinrichs B, et al.
Under detection of interstitial lung disease in juvenile systemic sclerosis (jSSc)
Arthritis Care & Research (Hoboken). 2020 Nov 3. doi: 10.1002/acr.24499.
Barreira SC, Melo AT, Ponte C, Khmelinskii N.
Macaroni sign and carotid occlusion in Takayasu's arteritis
Rheumatology (Oxford). 2020 Nov 3:keaa520. doi: 10.1093/rheumatology/keaa520.
Grimes D, Antonini A, Ferreira JJ, Sanchez-Ferro Á, Lynch T, Rascol O, Růžička E, Eggers C, Mestre TA.
Patient-centred management of Parkinson's disease
Lancet Neurology. 2020 Nov;19(11):887-888. doi: 10.1016/S1474-4422(20)30359-8.
Abadesso C, Pacheco S, Machado MC, Finley GA.
Pain in children and adolescents with sickle cell disease: multidimensional assessment
Journal of Pediatric Hematology and Oncology. 2020 Nov;42(8):455-462. doi: 10.1097/MPH.0000000000001941.
Baiocchi GL, Giacopuzzi S, Reim D, et al.
Incidence and grading of complications after gastrectomy for cancer using the GASTRODATA Registry: a European retrospective observational study.
Annals of Surgery. 2020 Nov;272(5):807-813. doi: 10.1097/SLA.0000000000004341.
Cruz-Machado AR, Rodrigues-Manica S, Silva JL, Alho I, Coelho C, Duarte J, Florêncio C, Pimentel-Santos FM, Tavares-Costa J, Vieira-Sousa E.
Effect of biologic disease-modifying anti-rheumatic drugs targeting remission in axial spondyloarthritis: systematic review and meta-analysis
Rheumatology (Oxford). 2020 Nov 1;59(11):3158-3171. doi: 10.1093/rheumatology/keaa268.
Smith SM, Dworkin RH, Turk DC, et al.
Interpretation of chronic pain clinical trial outcomes: IMMPACT recommended considerations
Pain. 2020 Nov;161(11):2446-2461. doi: 10.1097/j.pain.0000000000001952.
Gao D, David C, Rosa MM, Costa J, Pinto FJ, Caldeira D
The risk of mortality associated with opioid use in patients with acute heart failure: systematic review and meta-analysis
Journal of Cardiovascular Pharmacology. 2020 Nov 17. doi: 10.1097/FJC.0000000000000954.
Napolitano M, Franchi-Abella S, Damasio MB, Augdal TA, Avni FE, Bruno C, Darge K, Ključevšek D, Littooij AS, Lobo L, Mentzel HJ, Riccabona M, Stafrace S, Toso S, Woźniak MM, Di Leo G, Sardanelli F, Ording Müller LS, Petit P.
Practical approach to imaging diagnosis of biliary atresia, Part 1: prenatal ultrasound and magnetic resonance imaging, and postnatal ultrasound
Pediatric Radiology. 2020
André Silva
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andresilva@medicina.ulisboa.pt